Is the CTS5 a helpful decision-making tool in the extended adjuvant therapy setting? Kerstin Wimmer, Dominik Hlauschek, Marija Balic, Georg Pfeiler, Christian F Singer , Stefan Halper, Günther Steger, Christoph Suppan, Simon P Gampenrieder, Ruth Helfgott, Daniel Egle, Martin Filipits, Raimund Jakesz, Lidija Sölkner, Christian Fesl, Michael Gnant, Florian Fitzal, Richard Greil Breast Cancer Res Treat. 2024 Jan 25. doi: 10.1007/s10549-023-07186-6.
Ptotic versus Nonptotic Breasts in Nipple-sparing Mastectomy and Immediate Prepectoral Breast Reconstruction Edvin Ostapenko, Larissa Nixdorf, Yelena Devyatko, Ruth Exner, Pia Math, Kerstin Wimmer, Theresa Haeusler, Florian Fitzal Plast Reconstr Surg Glob Open. 2023 May; 11(5): e5032. Published online 2023 May 26. doi: 10.1097/GOX.0000000000005032
Prepectoral Versus Subpectoral Implant-Based Breast Reconstruction: A Systemic Review and Meta-analysis Edvin Ostapenko, Larissa Nixdorf, Yelena Devyatko, Ruth Exner, Kerstin Wimmer, Florian Fitzal Ann Surg Oncol. 2023; 30(1): 126–136. Published online 2022 Oct 16. doi: 10.1245/s10434-022-12567-0
Differential immunomodulatory effects of epirubicin/cyclophosphamide and docetaxel in breast cancer patients Kerstin Wimmer, Monika Sachet, Cristiano Ramos, Sophie Frantal, Hanna Birnleitner, Christine Brostjan, Ruth Exner, Martin Filipits, Zsuzsanna Bago-Horvath, Margaretha Rudas, Rupert Bartsch, Michael Gnant, Christian F Singer, Marija Balic, Daniel Egle, Rudolf Oehler, Florian Fitzal Exp Clin Cancer Res 2023 Nov 14;42(1):300. doi: 10.1186/s13046-023-02876-x.
The iTOP trial: Comparing immediate techniques of oncoplastic surgery with conventional breast surgery in women with breast cance - a prospective, controlled, single-center study Michael Bolliger, Pia Lanmüller, Michael Schuetz, Bernhard Heilig, Amadeus Windischbauer, Raimund Jakesz, Tanja Zehetgruber, Michael Gnant, Andreas Gleiss, Daniela Dörfler, Christian Singer, Rupert Bartsch, Werner Haslik, Giacomo Montagna, Florian Fitzal Int J Surg. Author manuscript; available in PMC 2023 Aug 1. Published in final edited form as: Int J Surg. 2022 Aug; 104: 106694. Published online 2022 Jun 1. doi: 10.1016/j.ijsu.2022.106694 PMCID: PMC10084682
Influence of Height on Risk and Outcome of Patients with Early Breast Cancer: A Pooled Analysis of 4,925 Patients from 5 Randomized Trials of the Austrian Breast and Colorectal Cancer Study Group (ABCSG) Simon P. Gampenrieder, Magdalena Pircher, Christian Fesl, Gabriel Rinnerthaler, Brigitte Mlineritsch, Sigrun Greil-Ressler, Günther G. Steger, Verena Sagaster, Florian Fitzal, Ruth Exner, Yelena Devyatko, Marija Balic, Herbert Stöger, Christoph Suppan, Thomas Bauernhofer, Christian F. Singer, Georg Pfeiler, Michael Seifert, Ruth Helfgott, Dietmar Heck, Holger Rumpold, Werner Kwasny, Ursula Wieder, Michael Gnant, Richard Greil Breast Care (Basel) 2022 Apr; 17(2): 137–145. Published online 2021 May 21. doi: 10.1159/000516157 PMCID: PMC9149458
Tailored axillary surgery in patients with clinically node-positive breast cancer: Pre-planned feasibility substudy of TAXIS (OPBC-03, SAKK 23/16, IBCSG 57-18, ABCSG-53, GBG 101). Weber WP, Matrai Z, Hayoz S, Tausch C, Henke G, Zwahlen DR, Gruber G, Zimmermann F, Seiler S, Maddox C, Ruhstaller T, Muenst S, Ackerknecht M, Kuemmel S, Bjelic-Radisic V, Kurzeder C, Újhelyi M, Vrieling C, Satler R, Meyer I, Becciolini C, Bucher S, Simonson C, Fehr PM, Gabriel N, Maráz R, Sarlos D, Dedes KJ, Leo C, Berclaz G, Dubsky P, Exner R, Fansa H, Hager C, Reisenberger K, Singer CF, Reitsamer R, Reinisch M, Winkler J, Lam GT, Fehr MK, Naydina T, Kohlik M, Clerc K, Ostapenko V, Fitzal F, Nussbaumer R, Maggi N, Schulz A, Markellou P, Lelièvre L, Egle D, Heil J, Knauer M. Breast. 2021 Sep 8;60:98-110. doi: 10.1016/j.breast.2021.09.004.
Favourable outcome of patients with breast cancer brain metastases treated with dual HER2 blockade of trastuzumab and pertuzumab. Bergen ES, Binter A, Starzer AM, Heller G, Kiesel B, Tendl-Schulz K, Bago-Horvath Z, Furtner J, Leitner J, Exner R, Fitzal F, Dieckmann K, Widhalm G, Preusser M, Berghoff AS, Bartsch R. Ther Adv Med Oncol. 2021 Apr 22;13:17588359211009002. doi: 10.1177/17588359211009002
Conventional versus reverse sequence of neoadjuvant epirubicin/cyclophosphamide and docetaxel: sequencing results from ABCSG-34 Rupert Bartsch, Christian F. Singer, Georg Pfeiler, Michael Hubalek, Herbert Stoeger, Angelika Pichler, Edgar Petru, Vesna Bjelic-Radisic, Richard Greil, Margaretha Rudas, Tea Maria Muy-Kheng, Viktor Wette, Andreas L. Petzer, Paul Sevelda, Daniel Egle, Peter C. Dubsky, Martin Filipits, Florian Fitzal, Ruth Exner, Raimund Jakesz, Marija Balic, Christoph Tinchon, Zsuzsanna Bago-Horvath, Sophie Frantal, Michael Gnant, for the Austrian Breast and Colorectal Cancer Study Group Br J Cancer. 2021 May 25; 124(11): 1795–1802. Published online 2021 Mar 24. doi: 10.1038/s41416-021-01284-2 PMCID: PMC8144560
Retrospective, Multicenter Analysis Comparing Conventional with Oncoplastic Breast Conserving Surgery: Oncological and Surgical Outcomes in Women with High-Risk Breast Cancer from the OPBC-01/iTOP2 Study. Fitzal F, Bolliger M, Dunkler D, Geroldinger A, Gambone L, Heil J, Riedel F, de Boniface J, Andre C, Matrai Z, Pukancsik D, Paulinelli RR, Ostapenko V, Burneckis A, Ostapenko A, Ostapenko E, Meani F, Harder Y, Bonollo M, Alberti ASM, Tausch C, Papassotiropoulos B, Helfgott R, Heck D, Fehrer HJ, Acko M, Schrenk P, Trapp EK, Gunda PT, Clara P, Montagna G, Ritter M, Blohmer JU, Steffen S, Romics L, Morrow E, Lorenz K, Fehr M, Weber WP. Ann Surg Oncol. 2021 Oct 13. doi: 10.1245/s10434-021-10809-1.
ASO Author Reflections: Impact of Resection Volume on Risk of Local Recurrence-The OPBC-01/iTOP2 Study. Montagna G, Weber WP, Geroldinger A, Fitzal F. Ann Surg Oncol. 2021 Sep 28. doi: 10.1245/s10434-021-10862-w.
Prepectoral versus subpectoral implant-based breast reconstruction after skin-sparing mastectomy or nipple-sparing mastectomy (OPBC-02/ PREPEC): a pragmatic, multicentre, randomised, superiority trial. Kappos EA, Schulz A, Regan MM, Moffa G, Harder Y, Ribi K, Potter S, Pusic AL, Fehr MK, Hemkens LG, Holzbach T, Farhadi J, Simonson C, Knauer M, Verstappen R, Bucher HC, Zwahlen D, Zimmermann F, Schwenkglenks M, Mucklow R, Shaw J, Bjelic-Radisic V, Chiorescu A, Chun YS, Farah S, Xiaosong C, Nigard L, Kuemmel S, Reitsamer R, Hauschild M, Fulco I, Tausch C, Fischer T, Sarlos D, Constantinescu MA, Lupatsch JE, Fitzal F, Heil J, Matrai Z, de Boniface J, Kurzeder C, Haug M, Weber WP. BMJ Open. 2021 Sep 2;11(9):e045239. doi: 10.1136/bmjopen-2020-045239.
The OncoMasTR Test Predicts Distant Recurrence in Estrogen Receptor-Positive, HER2-Negative Early-Stage Breast Cancer: A Validation Study in ABCSG Trial 8. Filipits M, Rudas M, Kainz V, Singer CF, Fitzal F, Bago-Horvath Z, Greil R, Balic M, Regitnig P, Halper S, Hulla W, Egle D, Barron S, Loughman T, O'Leary D, Gallagher WM, Hlauschek D, Gnant M, Dubsky P. Clin Cancer Res. 2021 Aug 11. doi: 10.1158/1078-0432.CCR-21-1023.
ESR1, PGR, ERBB2, and MKi67 mRNA expression in postmenopausal women with hormone receptor-positive early breast cancer: results from ABCSG Trial 6. Filipits M, Rudas M, Singer CF, Fitzal F, Bago-Horvath Z, Greil R, Balic M, Lax SF, Halper S, Hulla W, Wu NC, Liu X, Weidler J, Bates M, Hlauschek D, Gnant M, Dubsky P. ESMO Open. 2021 Aug;6(4):100228. doi: 10.1016/j.esmoop.2021.100228.
Duration of Adjuvant Aromatase-Inhibitor Therapy in Postmenopausal Breast Cancer. Gnant M, Fitzal F, Rinnerthaler G, Steger GG, Greil-Ressler S, Balic M, Heck D, Jakesz R, Thaler J, Egle D, Manfreda D, Bjelic-Radisic V, Wieder U, Singer CF, Melbinger-Zeinitzer E, Haslbauer F, Sevelda P, Trapl H, Wette V, Wimmer K, Gampenrieder SP, Bartsch R, Kacerovsky-Strobl S, Suppan C, Brunner C, Deutschmann C, Soelkner L, Fesl C, Greil R; Austrian Breast and Colorectal Cancer Study Group. N Engl J Med. 2021 Jul 29;385(5):395-405. doi: 10.1056/NEJMoa2104162.
Androgen Receptor is Expressed in Breast Cancer Brain Metastases. Bergen ES, Berghoff AS, Steindl A, Rajky O, Mercea PA, Kiesel B, Tendl-Schulz K, Bago-Horvath Z, Exner R, Fitzal F, Dieckmann K, Widhalm G, Steger GG, Preusser M, Bartsch R. Appl Immunohistochem Mol Morphol. 2021 Jun 14. doi: 10.1097/PAI.0000000000000952.
Conventional versus reverse sequence of neoadjuvant epirubicin/cyclophosphamide and docetaxel: sequencing results from ABCSG-34. Bartsch R, Singer CF, Pfeiler G, Hubalek M, Stoeger H, Pichler A, Petru E, Bjelic-Radisic V, Greil R, Rudas M, Muy-Kheng TM, Wette V, Petzer AL, Sevelda P, Egle D, Dubsky PC, Filipits M, Fitzal F, Exner R, Jakesz R, Balic M, Tinchon C, Bago-Horvath Z, Frantal S, Gnant M; Austrian Breast and Colorectal Cancer Study Group. Br J Cancer. 2021 May;124(11):1795-1802. doi: 10.1038/s41416-021-01284-2.
PAM-50 predicts local recurrence after breast cancer surgery in postmenopausal patients with ER+/HER2- disease: results from 1204 patients in the randomized ABCSG-8 trial. Fitzal F, Filipits M, Fesl C, Rudas M, Greil R, Balic M, Moinfar F, Herz W, Dubsky P, Bartsch R, Ferree S, Schaper C, Gnant M; Austrian Breast and Colorectal Cancer Study Group (ABCSG). Br J Surg. 2021 Apr 5;108(3):308-314. doi: 10.1093/bjs/znaa089.
Palbociclib with adjuvant endocrine therapy in early breast cancer (PALLAS): interim analysis of a multicentre, open-label, randomised, phase 3 study. Mayer EL, Dueck AC, Martin M, Rubovszky G, Burstein HJ, Bellet-Ezquerra M, Miller KD, Zdenkowski N, Winer EP, Pfeiler G, Goetz M, Ruiz-Borrego M, Anderson D, Nowecki Z, Loibl S, Moulder S, Ring A, Fitzal F, Traina T, Chan A, Rugo HS, Lemieux J, Henao F, Lyss A, Antolin Novoa S, Wolff AC, Vetter M, Egle D, Morris PG, Mamounas EP, Gil-Gil MJ, Prat A, Fohler H, Metzger Filho O, Schwarz M, DuFrane C, Fumagalli D, Theall KP, Lu DR, Bartlett CH, Koehler M, Fesl C, DeMichele A, Gnant M. Lancet Oncol. 2021 Feb;22(2):212-222. doi: 10.1016/S1470-2045(20)30642-2.
Patient satisfaction after breast cancer surgery : A prospective clinical trial. Leser C, Tan YY, Singer C, Zeillinger R, Fitzal F, Lehrner J, König D, Deutschmann C, Gschwantler-Kaulich D. Wien Klin Wochenschr. 2021 Jan;133(1-2):6-13. doi: 10.1007/s00508-020-01730-w.
Knowledge gaps in oncoplastic breast surgery. Weber WP, Morrow M, Boniface J, Pusic A, Montagna G, Kappos EA, Ritter M, Haug M, Kurzeder C, Saccilotto R, Schulz A, Benson J, Fitzal F, Matrai Z, Shaw J, Peeters MV, Potter S, Heil J; Oncoplastic Breast Consortium. Lancet Oncol. 2020 Aug;21(8):e375-e385. doi: 10.1016/S1470-2045(20)30084-X.
Prognostic Value of EndoPredict in Women with Hormone Receptor-Positive, HER2-Negative Invasive Lobular Breast Cancer. Sestak I, Filipits M, Buus R, Rudas M, Balic M, Knauer M, Kronenwett R, Fitzal F, Cuzick J, Gnant M, Greil R, Dowsett M, Dubsky P. Clin Cancer Res. 2020 Sep 1;26(17):4682-4687. doi: 10.1158/1078-0432.CCR-20-0260.
Impact of contemporary therapy- concepts on surgical morbidity in breast cancer patients: A retrospective single center analysis of 829 patients. Schlagnitweit P, Helfgott R, Theodosiadi S, Mascherbauer M, Petzer A, Geinitz H, Langsteger W, Emmanuel K, Fitzal F. Eur J Surg Oncol. 2020 Aug;46(8):1477-1483. doi: 10.1016/j.ejso.2020.04.034.
Immediate Breast Reconstruction. Kappos EA, Weber WP, de Boniface J, Harder Y, Heil J, Fitzal F, Matrai Z. Breast Care (Basel). 2020 Apr;15(2):188-191. doi: 10.1159/000505176.
Factors influencing agreement of breast cancer luminal molecular subtype by Ki67 labeling index between core needle biopsy and surgical resection specimens. Tendl-Schulz KA, Rössler F, Wimmer P, Heber UM, Mittlböck M, Kozakowski N, Pinker K, Bartsch R, Dubsky P, Fitzal F, Filipits M, Eckel FC, Langthaler EM, Steger G, Gnant M, Singer CF, Helbich TH, Bago-Horvath Z. Virchows Arch. 2020 Oct;477(4):545-555. doi: 10.1007/s00428-020-02818-4.
Primary surgery versus no surgery in synchronous metastatic breast cancer: patient-reported quality-of-life outcomes of the prospective randomized multicenter ABCSG-28 Posytive Trial. Bjelic-Radisic V, Fitzal F, Knauer M, Steger G, Egle D, Greil R, Schrenk P, Balic M, Singer C, Exner R, Soelkner L, Gnant M; ABCSG. BMC Cancer. 2020 May 6;20(1):392. doi: 10.1186/s12885-020-06894-2.
Clinically high-risk breast cancer displays markedly discordant molecular risk predictions between the MammaPrint and EndoPredict tests. Jahn SW, Bösl A, Tsybrovskyy O, Gruber-Rossipal C, Helfgott R, Fitzal F, Knauer M, Balic M, Jasarevic Z, Offner F, Moinfar F. Br J Cancer. 2020 Jun;122(12):1744-1746. doi: 10.1038/s41416-020-0838-2.
Efficacy and safety of the therapeutic cancer vaccine tecemotide (L-BLP25) in early breast cancer: Results from a prospective, randomised, neoadjuvant phase II study (ABCSG 34). Singer CF, Pfeiler G, Hubalek M, Bartsch R, Stöger H, Pichler A, Petru E, Bjelic-Radisic V, Greil R, Rudas M, Maria Tea MK, Wette V, Petzer AL, Sevelda P, Egle D, Dubsky PC, Filipits M, Fitzal F, Exner R, Jakesz R, Balic M, Tinchon C, Bago-Horvath Z, Frantal S, Gnant M; Austrian Breast & Colorectal Cancer Study Group. Eur J Cancer. 2020 Jun;132:43-52. doi: 10.1016/j.ejca.2020.03.018.
Impact of Surgical Margins in Breast Cancer After Preoperative Systemic Chemotherapy on Local Recurrence and Survival. Wimmer K, Bolliger M, Bago-Horvath Z, Steger G, Kauer-Dorner D, Helfgott R, Gruber C, Moinfar F, Mittlböck M, Fitzal F. Ann Surg Oncol. 2020 May;27(5):1700-1707. doi: 10.1245/s10434-019-08089-x.
Stromal coexpression of uPA/PAI-1 protein predicts poor disease outcome in endocrine-treated postmenopausal patients with receptor-positive early breast cancer. Singer CF, Filipits M, Jahn SW, Abete L, Jakesz R, Greil R, Bauernhofer T, Kwasny W, Seifert M, Fitzal F, Kastner M, Schmitt M, Moinfar F, Gnant M. Breast. 2019 Aug;46:101-107. doi: 10.1016/j.breast.2019.05.007.
Impact of Breast Surgery in Primary Metastasized Breast Cancer: Outcomes of the Prospective Randomized Phase III ABCSG-28 POSYTIVE Trial. Fitzal F, Bjelic-Radisic V, Knauer M, Steger G, Hubalek M, Balic M, Singer C, Bartsch R, Schrenk P, Soelkner L, Greil R, Gnant M; ABCSG. Ann Surg. 2019 Jun;269(6):1163-1169. doi: 10.1097/SLA.0000000000002771.
Prediction of Distant Recurrence Using EndoPredict Among Women with ER+, HER2- Node-Positive and Node-Negative Breast Cancer Treated with Endocrine Therapy Only. Filipits M, Dubsky P, Rudas M, Greil R, Balic M, Bago-Horvath Z, Singer CF, Hlauschek D, Brown K, Bernhisel R, Kronenwett R, Lancaster JM, Fitzal F, Gnant M. Clin Cancer Res. 2019 Jul 1;25(13):3865-3872. doi: 10.1158/1078-0432.CCR-19-0376.
Is breast implant-associated anaplastic large cell lymphoma a hazard of breast implant surgery? Fitzal F, Turner SD, Kenner L. Open Biol. 2019 Apr 26;9(4):190006. doi: 10.1098/rsob.190006.
Adjuvant denosumab in postmenopausal patients with hormone receptor-positive breast cancer (ABCSG-18): disease-free survival results from a randomised, double-blind, placebo-controlled, phase 3 trial. Gnant M, Pfeiler G, Steger GG, Egle D, Greil R, Fitzal F, Wette V, Balic M, Haslbauer F, Melbinger-Zeinitzer E, Bjelic-Radisic V, Jakesz R, Marth C, Sevelda P, Mlineritsch B, Exner R, Fesl C, Frantal S, Singer CF; Austrian Breast and Colorectal Cancer Study Group. Lancet Oncol. 2019 Mar;20(3):339-351. doi: 10.1016/S1470-2045(18)30862-3.
Continued Endocrine Therapy Is Associated with Improved Survival in Patients with Breast Cancer Brain Metastases. Bergen ES, Berghoff AS, Medjedovic M, Rudas M, Fitzal F, Bago-Horvath Z, Dieckmann K, Mader RM, Exner R, Gnant M, Zielinski CC, Steger GG, Preusser M, Bartsch R. Clin Cancer Res. 2019 May 1;25(9):2737-2744. doi: 10.1158/1078-0432.CCR-18-1968.